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Author SHA1 Message Date
coolneng 8ffa86a965
Elaborate on the project description in the README 2021-05-04 02:01:10 +02:00
coolneng 1f7b40d224
Remove redundant JDK dependency 2021-05-04 01:57:34 +02:00
2 changed files with 11 additions and 10 deletions

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@ -1,6 +1,13 @@
* locigenesis
locigenesis is a tool that generates an immune repertoire and runs it through a sequence reader simulation tool, to generate sequencing errors.
locigenesis is a tool that generates a human T-cell receptor (TCR), runs it through a sequence reader simulation tool and extracts CDR3.
The goal of this project is to generate both HVR sequences with and without sequencing errors, in order to create datasets for a Machine Learning algorithm.
** Technologies
- [[https://github.com/GreiffLab/immuneSIM/][immuneSIM]]: in silico generation of human and mouse BCR and TCR repertoires
- [[http://www.pegase-biosciences.com/curesim-a-customized-read-simulator/][CuReSim]]: read simulator that mimics Ion Torrent sequencing
** Installation

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@ -21,16 +21,10 @@ let
installPhase = ''
mkdir -pv $out/share/java $out/bin
cp -r ${src} $out/share/java/${name}
makeWrapper ${pkgs.jdk}/bin/java $out/bin/CuReSim --add-flags "-jar $out/share/java/${name}/${name}.jar"
makeWrapper ${jre}/bin/java $out/bin/CuReSim --add-flags "-jar $out/share/java/${name}/${name}.jar"
'';
};
in mkShell {
buildInputs = [
R
rPackages.immuneSIM
rPackages.Biostrings
rPackages.stringr
jdk
CuReSim
];
buildInputs =
[ R rPackages.immuneSIM rPackages.Biostrings rPackages.stringr CuReSim ];
}