Rename function arguments to improve readability
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@ -11,22 +11,22 @@ parse_data <- function(file) {
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return(list(sequences, vj_segments))
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return(list(sequences, vj_segments))
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}
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}
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match_id_sequence <- function(names, sequences, id) {
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match_id_sequence <- function(names, vdj_segments, id) {
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matches <- grep(names, pattern = id)
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matches <- grep(names, pattern = id)
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row <- matches[1]
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row <- matches[1]
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return(as.character(sequences[row]))
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return(as.character(vdj_segments[row]))
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}
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}
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get_vj_sequence <- function(sequences, names, vdj_segments) {
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get_vj_sequence <- function(metadata, names, vdj_segments) {
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metadata <- unlist(strsplit(sequences, split = " "))
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id_elements <- unlist(strsplit(metadata, split = " "))
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v_identifier <- metadata[2]
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v_identifier <- id_elements[2]
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j_identifier <- metadata[3]
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j_identifier <- id_elements[3]
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v_sequence <- match_id_sequence(names, vdj_segments, id = v_identifier)
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v_sequence <- match_id_sequence(names, vdj_segments, id = v_identifier)
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j_sequence <- match_id_sequence(names, vdj_segments, id = j_identifier)
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j_sequence <- match_id_sequence(names, vdj_segments, id = j_identifier)
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return(c(v_sequence, j_sequence))
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return(c(v_sequence, j_sequence))
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}
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}
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fetch_vj_sequences <- function(vdj_segments, sequences) {
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fetch_vj_sequences <- function(sequences, vdj_segments) {
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vj_sequences <- mclapply(names(sequences),
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vj_sequences <- mclapply(names(sequences),
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names(vdj_segments),
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names(vdj_segments),
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vdj_segments,
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vdj_segments,
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@ -45,8 +45,9 @@ align_sequence <- function(sequence, vdj_segment) {
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))
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))
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}
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}
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# TODO Extract CDR3
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get_hvr_sequences <- function(sequences, vdj_segments) {
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get_hvr_sequences <- function(sequences, vdj_segments) {
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vj_sequences <- fetch_vj_sequences(vdj_segments, sequences)
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vj_sequences <- fetch_vj_sequences(sequences, vdj_segments)
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v_alignment <- parallel::mcmapply(sequences,
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v_alignment <- parallel::mcmapply(sequences,
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vj_sequences[1],
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vj_sequences[1],
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FUN = align_sequence
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FUN = align_sequence
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